Bextra Information:
Bextra attracts the spotlight for blatant commercial use of academic journals.
Like the other COX-2 Inhibitors Vioxx
and Celebrex, Bextra (valdecoxib) is prone to major side effects.
Drug names:
Bextra (valdecoxib)
Bextra approved medical usage:
Bextra is a prescription drug used in the treatment of osteoarthritis , rheumatoid
arthritis, and painful menstruation and menstrual symptoms. Bextra is classified
as a nonsteroidal anti-inflammatory drug, or NSAID, and bextra should not
be taken by anyone allergic to these types of medications.
Bextra dosage:
10mg and 20mg tablets
Bextra side effects:
Anaphylaxis, Angioedema and serious skin reactions including Erythema Multiforme,
Exfoliative Dermatitis, Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
Bextra produced by:
Pharmacia (Pfizer) and G. D. Searle & Company by brand name bextra
Bextra patient presentation:
Allergic reaction in a variety of body parts that may be fatal; swelling of
tissue just below skin or peeling/blistering of skin; minor or major eruptions
of the skin; severe inflammation of the entire skin, different from Skin Rash
Bextra Class Action and Litigation status:
Public Citizen focus on off-label marketing using refereed, academic
journal as vehicle. Pharmacia is sued over promotion of off-label use of pain-killer
Bextra.
A consumer group has filed lawsuit against Pharmacia (Pfizer) for illegal
Off-Label promotion of the COX-2 inhibitor Bextra (valdecoxib). Pharmacia
hired the clinical testing group Scirex to study the use of Bextra in acute
pain associated with impacted molars; the results were published in the Journal
of the American Dental Association for which continuing medical education
credit was available. Public Citizen criticized the use of refereed, academic
journals for commercial promotion of off-label use of bextra.
Daniels SE et al., The analgesic efficacy of valdecoxib vs. oxycodone/acetaminophen
after oral surgery. J Am Dent Assoc. 2002 May;133(5):611-21; quiz 625.
Further bextra information:
Contact www.drugintel.com
Bextra Vioxx Celebrex
Bextra, vioxx
and celebrex are all NSAID's or Cox-2 inhibitors. Because bextra, vioxx and
celebrex have the same mechanism of action, it was feared that this groug
of drugs would all have the same side effect of increased heart risk. So far,
there is no hard evidence that Celebrex increases heart risk. On the contrary
with Celebrex there is some evidence that it is more heart-friendly than bextra
or Vioxx.
Celebrex doesn't raise blood pressure at high doses and there seems to be
no increase in heart disease events from the many studies conducted.
Ref: www.thedoctorslounge.net
Bextra Side Effects
This is not a complete list of bextra side effects. Your doctor should discuss
with you a more complete list of bextra side effects.
Bextra side effects can include:
• Indigestion
• Nausea
• Stomach pain
• Upper respiratory tract infection
• Diarrhea
• Headache
• Rarely serious ulcers and stomach bleeding have occurred while taking Bextra.
Bextra Class Action
For more bextra lawyers and bextra litigation, please take a look at bextra
litigation. Parts of this bextra facts and information were taken from
Wikipedia, drug information
See Also Vioxx
This document is provided solely for educational and informational purposes. Be sure to consult your doctor before making any major medical decision.