What is Enoxaparin (commonly mispelled Enooxaparin) prescribed for?
Enoxaparin (Eno0xaparin) is used to prevent blood clots in the legs. This most commonly effects patients that are on bed rest due to lower body surgeries. When used with apririn, Enoxaparin can help prevent possible heart attack complications. Enoxaprin medication works by stopping the formation of substances in the body that create blood clots.
In actual science terms enoxaparin binds to and accelerates the activity of Antithrombin III. By activating Antithrombin III enoxaparin preferentially potentiates the inhibition of coagulation factors Xa and IIa. The anticoagulant effect of enoxaparin can be directly correlated to its ability to inhibit factor Xa. Factor Xa catalyzes the conversion of prothrombin to thrombin, so enoxaparin’s inhibition of this process results in decreased thrombin and ultimately the prevention of fibrin clot formation.
In the United Kingdom, enoxaparin is approved for the following indications:
· The prophylaxis of thromboembolism disorders of venous origin, in particular those which may be associated with orthopaedic surgery.
· The prophylaxis of venous thromboembolism (VTE) in medical patients bedridden due to acute illness.
· The treatment of venous thromboembolism disease (VTED) presenting with deep vein thrombosis (DVT), pulmonary embolism (PE) or both.
· The treatment of unstable angina (UA) and non-Q-wave myocardial infarction (NQMI), administered concurrently with aspirin.
The prevention of thrombus formation in the extracorpreal circulation during haemodialysis.
Possible Side Effects Of Enoxaprin (Enoxaprin) May Include:
· Bleeding
· Thrombocytopenia, i.e. can be asssociated with heparin-induced thrombocytopenia
· Pain, bruising or irritation; hard, inflamed nodules or an itchy red rash at the injection site
· Symptoms similar to those of hayfever
· Abdominal/chest pain
Headache
If you experience a serious side effect while taking enoxaprin, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/report.htm] or by phone [1-800-332-1088].